Clinical-grade hormonal intelligence at the point of care.
Yohafly's healthcare programme brings hormonal diagnosis and fertility-stage tracking to women in remote and underserved regions — building on SERB POWER–funded research (Grant No. SPG/2022/000681) into a non-invasive, self-administered system.
This system is under active research and development (project timeline to 2026) and is not yet a commercially available or regulatory-cleared medical device.
A Common, Under-Diagnosed Barrier to Fertility
PCOS is among the most prevalent drivers of infertility, affecting an estimated 5–18% of women of reproductive age, with prevalence in India reported between 3.7% and 22.5%. Diagnosis depends on detecting hormonal imbalance, traditionally requiring repeated clinic visits and lab blood work — a barrier for women far from diagnostic infrastructure.
Phase I — Built & Bench-Validated
Phase I (Dec 2023 – Mar 2025) delivered a complete point-of-care pipeline, built and bench-tested.
Serum-Separation Centrifuge
A 3D-printed, battery-powered portable centrifuge enabling reliable serum separation outside a central lab.
Microfluidic ELISA Cassette
An automated microfluidic cassette that runs the ELISA assay on-device for AMH, LH, and FSH.
Spectrophotometric Readout
A miniaturised ~450 nm spectrophotometric module with Beer–Lambert firmware for AMH/LH/FSH quantification.
Cloud Web App
A cloud web app for reports, trend tracking, and teleconsultation, built on Yohafly's low-power, offline-capable stack.
Bench validation: AMH 1.82 ng/mL · FSH 3.11 mIU/mL · LH 1.23 mIU/mL, benchmarked against Roche Diagnostics — bench results, not a clinical or regulatory claim.
Phase II — In Development (Target Jul–Sep 2026)
Phase II adds label-free electrochemical biosensing, on-device AI, and a multi-hormone panel — extending the Phase I platform toward field deployment.
EIS Biosensing
Label-free electrochemical impedance spectroscopy (EIS) biosensing on antibody-functionalised graphene screen-printed electrodes, for a multi-hormone panel (AMH/LH/FSH/testosterone) from a single fingerprick.
AI/ML Risk Prediction
PCOS risk prediction from impedance features plus age, BMI, and LH:FSH ratio. Models are currently being trained on simulated data, pending clinical validation.
Mobile App & Teleconsultation
A Tamil/English mobile app covering ANC/PNC tracking and teleconsultation, paired with IoT dashboards for remote follow-up.
AMTZ Integration & Village Deployment
Integration and benchmarking at AMTZ, followed by deployment across 15 villages in Trichy District.
Designed for Offline, Edge-AI Operation
The programme is designed for on-device processing and offline capability, so the system can work where connectivity and clinical staff are scarce — consistent with the ESP32 / TinyML stack used across Yohafly's products, including the flagship Portable Hormone Analyser.
Beyond the Fertility-Stage Programme
Dry Eye Disease Wearable (Observant)
An ESP32-BLE, canthus-mounted wearable sensing device designed to monitor indicators associated with Dry Eye Disease, supporting earlier detection and ongoing management.
Point-of-Care Rural Diagnostics
Compact diagnostic devices engineered for primary-care and rural settings where centralized lab access is limited, enabling on-site results without specialist infrastructure.
Remote Patient Monitoring
Connected monitoring tools that extend follow-up care beyond the clinic, built on the same low-power, offline-capable connectivity stack used across Yohafly's devices.
Backed by research: SERB POWER Grant SPG/2022/000681, Kongunadu College of Engineering and Technology — PI Dr. Yogapriya Jaganathan; Co-Is Dr. C. Saravanabhavan and Dr. Preethi Palanisamy (2023–2026).
The team's work, "An Integrated Framework for Women's Fertility Stage Analysis Using AI and IoT-Driven Technologies," was published in the ICEIE 2024 proceedings (ISBN 978-93-6163-096-5), funded by DST-SERB. Dr. Yogapriya also received the Best Keynote Speaker award at the 9th Annual Congress on PCOS and Fertility, London, 27–28 Nov 2025.
View grant details in Research & Grants → · See the research gallery →
Award & Industry Recognition
Best Keynote Speaker Award
Dr. Yogapriya received the Best Keynote Speaker Award at the 9th Annual Congress on PCOS and Fertility, London (27–28 Nov 2025) — formally acknowledged by ANRF, with a Certificate of Recognition from Conference Series (UK) and five indexed journals.
AMTZ Medical Robotics Hackathon
Selected among the top 9 at the First Global Hackathon on Medical Robotics (WHIF, AMTZ Visakhapatnam, 12–13 Dec 2025), leading to a confirmed 1-year incubation at the AMTZ Robotics Healthcare Centre.
Infosys TechZooka 2025
Participated in Infosys TechZooka / Technology Summit 2025 (MCity), showcasing the Phase I prototype to industry.
Grounded in Clinical Practice
Alongside lab and bench testing, the team has consulted endocrinologists, fertility specialists, and diagnostic laboratories to benchmark the prototype against established reference assays (including TSH and AMH ELISA) and to align the design with real-world clinical workflows. This consultation is ongoing as the system moves toward clinical validation.
Engaging Clinicians Across South India
The research team has engaged with fertility specialists, endocrinologists, and diagnostic labs across Tamil Nadu, Karnataka, and Kerala to ground the device's design in real clinical practice.
How This Fits the Yohafly Platform
The Portable Hormone Analyser remains Yohafly's flagship product and primary near-term focus. The healthcare programme on this page represents the broader diagnostic-platform context that the Analyser is built within — sharing its sensor design discipline, embedded AI/firmware, and clinical-grade software approach. These are presented as supporting platform context, not as a repositioning away from the Analyser.
Discuss a Healthcare Deployment or Collaboration
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